Product Name :
Anti-TfR1, Human antibody
Applications:
ELISA,Flow Cyt
Reactivity :
Human
Conjugate:
Unconjugated
Advantages :
High lot-to-lot consistencyIncreased sensitivity and higher affinityAnimal-free production
Description:
| Description: Anti-TfR1, Human antibody is designed for detecting human TfR1 specifically. Based on ELISA and/or FCM, Anti-TfR1, Human antibody reacts with human TfR1 specifically. | Immunogen: Recombinant human TfR1 | Host: Alpaca pacous | Isotype: Human IgG1 | Conjugate: Unconjugated | Specificity: Human TfR1 | Purity: Recombinant Expression and Affinity purified | Concentration: 1mg/ml | Formation: Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol | Storage: Store at –20 °C, (Avoid freeze / thaw cycles) | Background:Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes.{{869998-49-2} MedChemExpress|{869998-49-2} Technical Information|{869998-49-2} Purity|{869998-49-2} manufacturer} Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.
Description2 :
Anti-TfR1, Human antibody is designed for detecting human TfR1 specifically.{{69075-42-9} MedChemExpress|{69075-42-9} Protocol|{69075-42-9} In stock|{69075-42-9} supplier} Based on ELISA and/or FCM, Anti-TfR1, Human antibody reacts with human TfR1 specifically.PMID:30000836
Immunogen:
Recombinant human TfR1
Host :
Alpaca pacous
Isotype:
Human IgG1
Purity :
Recombinant Expression and Affinity purified
Buffer :
Storage :
Store at –20 °C, (Avoid freeze / thaw cycles)
Function:
ELISA: 1:4,000-1:10000Flow Cytometry：1:200-1:1000Dilution factors are presented in the form of a range because the optimal dilution is a function of many factors, such as antigen density, permeability, etc. The actual dilution used must be determined empirically.