Product Name: FAM151A Polyclonal Antibody, Cy7 Conjugated
Applications: IF(IHC-P)
Reactivity: Human, Mouse, Rat
Conjugation: Cy7
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human FAM151A
Clonality: Polyclonal
CAS NO: 956104-40-8
product targets : Leukotriene Receptor inhibitors
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: MGC37700; 2010309H15Rik; C1orf179; Family with sequence similarity 151, member A; Hypothetical protein LOC313430; MGC27169; MGC94145; OTTMUSP00000008558; Protein FAM151A; RP23-97O7.7; F151A_HUMAN.
Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The FAM151A gene product has been provisionally designated FAM151A pending further characterization.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20458144?dopt=Abstract