Product Name: DUSP2 Polyclonal Antibody, Cy5.5 Conjugated
Applications: IF(IHC-P)
Reactivity: Human, Mouse, Rat
Conjugation: Cy5.5
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human DUSP2
Clonality: Polyclonal
CAS NO: 22662-39-1
Product: GNE-317
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: Dual specicity phosphatase 2; Dual specicity protein phosphatase 2; Dual specicity protein phosphatase PAC 1; DUSP 2; PAC 1; PAC1; Serine/threonine specic protein phosphatase; DUS2_HUMAN.
Background: DUSP2 is a dual-specific thr/tyr phosphatase that is a physiologically relevant MAP kinase phosphatase. The gene is located on 2q11.2-q11 and contains 4 exons that span approximately 2.3kb. Under specific stress conditions, p53 regulates transcription of PAC1 through a new p53-binding site, and that PAC1 is necessary and sufficient for p53-mediated apoptosis.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/15231645