Product Name: DOK5 Polyclonal Antibody, Cy7 Conjugated
Applications: FCM, IF(IHC-P), IF(IHC-F)
Reactivity: Human, Mouse, Rat
Conjugation: Cy7
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human DOK5/IRS6
Clonality: Polyclonal
CAS NO: 33564-30-6
Product: DL-Xylose
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: IRS6; IRS-6; C2orf18; Docking protein 5; Downstream of tyrosine kinase 5; Insulin receptor substrate 6; DOK5
Background: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18455128