Product Name: DMTF1 Polyclonal Antibody, Cy5.5 Conjugated
Applications: IF(IHC-P)
Reactivity: Human, Mouse, Rat
Conjugation: Cy5.5
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human DMTF1
Clonality: Polyclonal
CAS NO: 912288-64-3
Product: SGC707
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: Cyclin D binding Myb like transcription factor 1; cyclin D binding myb like transcription factor 1D interacting myb like protein; Cyclin D interacting Myb like protein 1; Cyclin-D-binding Myb-like transcription factor 1; Cyclin-D-interacting Myb-like protein 1; D interacting myb like protein; DMP1; DMTF; dmtf1; DMTF1_HUMAN; hDMP1; hDMTF1; mDmp1.
Background: Transcriptional activator which activates the CDKN2A/ARF locus in response to Ras-Raf signaling, thereby promoting p53/TP53-dependent growth arrest. Binds to the consensus sequence 5-CCCG[GT]ATGT-3. Isoform 1 may cooperate with MYB to activate transcription of the ANPEP gene. Isoform 2 may antagonize transcriptional activation by isoform 1.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/11078189