Product Name: CXCR2/CD182 Polyclonal Antibody, Cy3 Conjugated
Applications: IF(IHC-P), IF(ICC)
Reactivity: Human, Mouse, Rat
Conjugation: Cy3
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human CXCR2
Clonality: Polyclonal
CAS NO: 29767-20-2
Product: LCL161
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: CD182; IL8R2; IL8RA; IL8RB; CMKAR2; CDw128b; C-X-C chemokine receptor type 2; CXC-R2; CXCR-2; GRO/MGSA receptor; High affinity interleukin-8 receptor B; IL-8R B; IL-8 receptor type 2; CXCR2
Background: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
PubMed ID:http://jpet.aspetjournals.org/content/61/2/148