Name :
ADAM8/CD156a Protein
Description :
ADAM8, also known as CD156, is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM8 is possiblely involved in extravasation of leukocytes As a metalloprotease, ADAM8 also may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma.
Species :
Human
Uniprotkb :
HEK293
Tag :
His
Synonyms :
CD156, MS2, CD156a, ADAM metallopeptidase domain 8
Construction :
A DNA sequence encoding the human ADAM8 (AAI15405.1) (Met1-Ser653) was expressed with a polyhistidine tag at the C-terminus.
Protein Purity :
> 95 % as determined by SDS-PAGE
Molecular Weight :
Approxiamtely 71 kDa
Endotoxin :
Formulatione :
Supplied as sterile 12. 5 mM Tris, 5 mM CaCl2, 75 mM NaCl, 50% glycerol, pH 7.5. Please contact us for any concerns or special requirements. Please refer to the specific buffer information in the hard copy of CoA.
Reconstitution :
A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping :
Solution. It is shipped out with blue ice.
Research Background :
ADAM8, also known as CD156, is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM8 is possiblely involved in extravasation of leukocytes As a metalloprotease, ADAM8 also may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma.
References and Literature :
1. Yoshiyama K.,et al.,(1997), CD156 (human ADAM8): expression, primary amino acid sequence, and gene location. Genomics 41:56-62. 2. Ota T.,et al., (2004), Complete sequencing and characterization of 21,243 full-length human cDNAs.Nat. Genet. 36:40-45. 3. Deloukas P.,et al.,(2004), The DNA sequence and comparative analysis of human chromosome 10.Nature 429:375-381.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
Arp3 Antibody web Sacubitril References PMID:34844329 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com