Product Name: eNOS (Ser1177) Polyclonal Antibody, HRP Conjugated
Applications: WB, IHC-P
Reactivity: Human, Mouse, Rat, Rabbit
Conjugation: HRP
Host: Rabbit
Sourcr: KLH conjugated synthetic phosphopeptide derived from human eNOS around the phosphorylation site of Ser1177
Clonality: Polyclonal
CAS NO: 1228585-88-3
Product: Otenabant (Hydrochloride)
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store at 4°C for 12 months.
Synonyms: eNOS; ECNOS; Nitric oxide synthase, endothelial; Constitutive NOS; cNOS; EC-NOS; Endothelial NOS; NOS type III; NOSIII; NOS3
Background: Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. Isoform eNOS13C: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19703992?dopt=Abstract