Product Name: FCAR Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
Applications: IF(IHC-P)
Reactivity: Human
Conjugation: ALEXA FLUOR® 594
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human FCAR
Clonality: Polyclonal
CAS NO: 312756-74-4
Product: PRE-084 (hydrochloride)
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: CD89; Fc alpha receptor; FCAR; FCAR_HUMAN; IgA Fc receptor; Immunoglobulin alpha Fc receptor.
Background: Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production. Tissue specificity; Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17641041?dopt=Abstract