Product Name: EGFR5 Polyclonal Antibody
Applications: WB, IHC-P, IF(IHC-P)
Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human EGFR5/CLEC14A
Clonality: Polyclonal
CAS NO: 1211443-80-9
Product: NBI-74330
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Synonyms: CEG1; EGFR-5; C14orf27; C-type lectin domain family 14 member A; Epidermal growth factor receptor 5; CLEC14A; EGFR5; UNQ236/PRO269
Background: This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This family member plays a role in cell-cell adhesion and angiogenesis. It functions in filopodia formation, cell migration and tube formation. Due to its presence at higher levels in tumor endothelium than in normal tissue endothelium, it is considered to be a candidate for tumor vascular targeting.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25677180?dopt=Abstract