Product Name: DOK2 (Tyr351) Polyclonal Antibody, Cy5 Conjugated
Applications: IF(IHC-P)
Reactivity: Human, Mouse
Conjugation: Cy5
Host: Rabbit
Sourcr: KLH conjugated synthetic phosphopeptide derived from mouse p56Dok2 around the phosphorylation site of (Tyr351)
Clonality: Polyclonal
CAS NO: 80418-24-2
Product: Buspirone (hydrochloride)
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: DokR; Frip; Docking protein 2; Dok-related protein; Dok-R; Downstream of tyrosine kinase 2; IL-four receptor-interacting protein; p56(dok-2); Dok2
Background: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/6292718