Product Name: DOK2 (Tyr139) Polyclonal Antibody, Cy5.5 Conjugated
Applications: IF(IHC-P)
Reactivity: Human, Mouse, Rat
Conjugation: Cy5.5
Host: Rabbit
Sourcr: KLH conjugated synthetic phosphopeptide derived from human p56Dok2 around the phosphorylation site of Tyr139
Clonality: Polyclonal
CAS NO: 37693-01-9
Product: ARV-825
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: DOK2 Tyr139; p-DOK2 Tyr139; Docking protein 2 56kDa; Docking protein 2 antibody DOK 2; DOK R; Downstream of tyrosine kinase 2; p56dok 2; p56dok 2; p56DOK; p56dok2
Background: The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008]
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/16882016