Product Name: DIO2 Polyclonal Antibody, FITC Conjugated
Applications: IF(IHC-P)
Reactivity: Human, Mouse, Rat
Conjugation: FITC
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human DIO2
Clonality: Polyclonal
CAS NO: 2061980-01-4
Product: Argipressin
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: 5DII; D2; Deiodinase, iodothyronine, type II; DIOII; ITDI2; SelY; Thyroxine deiodinase, type II; TXDI2; Type 2 DI; Type II 5 deiodinase; Type II iodothyronine deiodinase.
Background: DIO2 belongs to the iodothyronine deiodinase family and is responsible for the deiodination of T4 (3,5,3,5-tetraiodothyronine) into T3 (3,5,3-triiodothyronine). It is essential for providing the brain with appropriate levels of T3 during the critical period of development. DIO2 is expressed in heart, skeletal muscle, placenta, fetal brain and several regions of the adult brain. There are two named isoforms.
PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/27667686