Product Name: DBF4B Polyclonal Antibody
Applications: WB, IHC-P, IF(IHC-P)
Reactivity: Human
Conjugation: Unconjugated
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human DBF4B/ASKL1
Clonality: Polyclonal
CAS NO: 79517-01-4
Elafibranor
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Synonyms: Activator of S phase kinase like protein 1; ASK like protein 1; ASKL1; chb; Chfon homolog B; DBF 4B; DBF4 homolog B S. cerevisiae; DBF4 homolog B; Dbf4 related factor 1; DRF1; Protein DBF4 homolog B; ZDBF1B; Zinc finger DBF type containing 1B; DBF4B_HUMAN.
Background: DBF4B is a regulatory subunit for CDC7, a serine-threonine kinase which links cell cycle regulation to genome duplication. The complex CDC7-DBF4B selectively phosphorylates the MCM2 subunit at Ser-40 and then is involved in regulating the initiation of DNA replication during cell cycle. DBF4B localizes to the nucleus and its expression is cell cycle-regulated.
PubMed ID:http://jpet.aspetjournals.org/content/94/1/1