Product Name: DACH2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated
Applications: IF(IHC-P)
Reactivity: Human, Mouse, Rat
Conjugation: ALEXA FLUOR® 350
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human DACH2
Clonality: Polyclonal
CAS NO: 289499-45-2
Product: PDE-9 inhibitor
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: DACH 2; dachshund 2; Dachshund homolog 2 Drosophila; Dachshund homolog 2; Dachshund2; FLJ31391; HGNC:16814; MGC138545.
Background: DACH2 is a transcription factor that is involved in regulation of organogenesis. It seems to be a regulator for SIX1 and SIX6 and may act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter. It probably binds to DNA via its DACH box-N domain.
PubMed ID:http://jpet.aspetjournals.org/content/86/1/22