Product Name: CUEDC2 Polyclonal Antibody, HRP Conjugated
Applications: WB, IHC-P
Reactivity: Human, Mouse, Rat
Conjugation: HRP
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human CUE domain containing 2
Clonality: Polyclonal
CAS NO: 870061-27-1
Product: CC-401
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store at 4°C for 12 months.
Synonyms: C10orf66; bA18I14.5; CUE domain-containing protein 2; CUEDC2; HOYS6
Background: Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism.
PubMed ID:http://jpet.aspetjournals.org/content/54/4/398